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What is Intrinsic Dissolution and why is it important?

Posted by Pam Bialiy on

What is Intrinsic Dissolution and why is it important?

  The following article has been authored by John Heaney. Intrinsic dissolution is a specific niche of dissolution testing often reserved for early R&D.  The purpose is to provide scientists with an idea of the solubility of the API they’re studying.  This data can be invaluable as it will help determine the excipients required to develop an oral dosage form. There are 2 types of methods for this.  The first is a Rotating Disk (often called the Wood’s Apparatus) and the second is Stationary Disk.  In both cases a pellet of the pure drug is pressed into a drug compact...

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