News — low solubility
Why use APP 4?
Posted by Pam Bialiy on
The following article has been authored by John Heaney. Like the reciprocating cylinder (Apparatus 3), the flow-through diffusion cell (Apparatus 4) is quite rare compared to baskets (Apparatus 1) and paddles (Apparatus 2). But there are some distinct advantages to flow-through cell that can make it a boon to certain formulations. The design of the flow-through cell consists of a cell with specific dimensions with the dissolution media fed through it by a pump. The dissolution media is typically stored in a reservoir. The media can be recirculated which is referred to as a closed-system; or constantly dispensed and collected...