News — calibration
ASTM/Enhanced Mechanical Calibration vs Prednisone PVT- Which is better for my lab?
Posted by Pam Bialiy on
The following article has been authored by John Heaney. The debate about the prednisone performance verification test (PVT) versus the ASTM enhanced mechanical calibration has gone on since the inception of ASTM chapter 2503. Both are different means of providing an answer to the same question,” Is my dissolution tester suitable for use and can I trust the data from it?” The prednisone PVT is typically performed after a mechanical qualification of the dissolution tester which, if one follows USP 711, has wider tolerances for passing than ASTM 2503. However, if one follows the suggestions in USP Guideline on...